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Providence Hospital and Medical Centers

September 2005 

Monthly Cystic Fibrosis Newsletter

Julie Feldman MPH RD, Clinical Dietitian

   

How Sweet It Is?

As summer nears its end, the smell of cider and apples begins to fill the air. It is officially Cider Mill season. As a dietitian I have to tout the amazing health benefits of apples for not just CF patients but everyone. I am always asking all of the CF patients in clinic about their fiber intake and most of you just laugh. Well at this time of year there is no excuse for not getting enough fiber. One apple provides 5 grams of fiber, nearly a quarter of your daily requirements. One note for those of you feeling less than 100%, consuming un-pasteurized products like apple cider is not recommended for those with weakened immune systems as they may contain food borne illnesses that your body can’t fight against.

   

Cooking up a Cure

Scientists have created a "cookbook" for a type of DNA delivery systems that will assist in the safe and effective delivery of gene therapy. By utilizing knowledge of physics, scientists have discovered how different structures incorporate into DNA in different ways. Delivering DNA to the proper location and getting the right amount of DNA _expression without killing innocent cells has become the Achilles' heel in DNA delivery. The researchers at the University of Illinois may really be on to something when it comes to cooking up something new!

   

A Vaccine for Your Health

Solvay Pharmaceuticals and Berna Biotech Ltd announced this week that they have signed a commercialization and license agreement for Aerugen, a vaccine for the prevention of Pseudomonas aeruginosa (PA) infection in Cystic Fibrosis (CF) patients.

This new product is just another on the list of Solvay’s CF product list. Aerugen has a particularly high value in the treatment of CF patients, for whom PA infection is a major cause of death.

The vaccine Aerugen will be developed by Berna Biotech. The product has obtained orphan drug designation in the U.S. Berna will submit the U.S. Food and Drug Administration (FDA) file and the launch in the U.S. is expected to take place by 2009.

   

Hip Cells For Your Lungs

Tulane University has been granted $9.5 million to study the use of adult stem cells to treat lung diseases such as emphysema, asbestos exposure and cystic fibrosis. The hope is stem cells can repair the lining of the lungs damaged by cystic fibrosis.
Clinical trials are expected to begin in two years. If tests prove successful it should take only 90 days after bone marrow is extracted from patients to produce stem cells for treatment.
The stem cells will be administered to the patient through an injection, IV or nasal spray.

   

A Cider Mill Recipe!

Since the cider mill is on all of our minds. I though I would give you a sweet and wonderful way to enjoy your favorite apples.

Apple Pie Cake

 

Serves 6

 

 

 

 

2

cups all-purpose flour

 

 

1

cup packed light-brown sugar

 

 

2

teaspoons ground cinnamon

 

 

1

cup (2 sticks) unsalted butter

 

 

5

pounds tart apples, such as Granny Smith (about 12)

 

 

2

tablespoons freshly squeezed lemon juice

 

 

1.   In a large bowl, combine the flour, brown sugar, and 1 teaspoon cinnamon. Using an electric mixer or a pastry cutter, cut in the butter until the mixture forms pea-size pieces. Press two-thirds of the crumb mixture into the bottom and 1 inch up the sides of a 9-inch springform pan.

 

 

2.   Preheat the oven to 350°. Core and peel the apples. Cut into thin slices, and place in a large bowl. Toss the apple slices with the remaining teaspoon cinnamon and the lemon juice. Arrange apples in the prepared pan; they will come up over the sides of the pan. Sprinkle the remaining crumb mixture over the apples.

 

 

3.   Place pan on an aluminum foil–lined baking sheet, and bake until cooked through and golden brown on top, about 1 hour and 15 minutes. Run a knife around the edge of the pan, and let the cake cool in the pan to set. Serve, or refrigerate for 2 hours to set more firmly. Serve at room temperature.


All issues of Living Your Best Life : May, June, Aug-Sept, Oct, Nov-Dec 2001
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