| Providence Hospital and Medical
Centers
September 2005 |
Monthly
Cystic Fibrosis Newsletter
Julie Feldman MPH RD, Clinical Dietitian |
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How Sweet It Is?
As summer nears its end, the smell of cider and apples
begins to fill the air. It is officially Cider Mill season. As a dietitian
I have to tout the amazing health benefits of apples for not just CF
patients but everyone. I am always asking all of the CF patients in clinic
about their fiber intake and most of you just laugh. Well at this time
of year there is no excuse for not getting enough fiber. One apple provides
5 grams of fiber, nearly a quarter of your daily requirements. One note
for those of you feeling less than 100%, consuming un-pasteurized products
like apple cider is not recommended for those with weakened immune systems
as they may contain food borne illnesses that your body can’t fight
against. |
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Cooking up a Cure
Scientists have created a "cookbook" for a type of DNA delivery
systems that will assist in the safe and effective delivery of gene therapy.
By utilizing knowledge of physics, scientists have discovered how different
structures incorporate into DNA in different ways. Delivering DNA to
the proper location and getting the right amount of DNA _expression without
killing innocent cells has become the Achilles' heel in DNA delivery.
The researchers at the University of Illinois may really be on to something
when it comes to cooking up something new!
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A
Vaccine for Your Health
Solvay Pharmaceuticals and
Berna Biotech Ltd announced this week that they have signed a commercialization
and license agreement for Aerugen, a vaccine for the prevention
of Pseudomonas
aeruginosa (PA)
infection in Cystic Fibrosis (CF) patients.
This new
product is just another on the list of Solvay’s CF product
list. Aerugen has a particularly high value in the treatment of CF
patients, for whom PA infection is a major cause of death.
The vaccine
Aerugen will be developed by Berna Biotech. The product has obtained
orphan drug designation in the U.S. Berna will submit the U.S.
Food and Drug Administration (FDA) file and the launch in the U.S. is
expected to take place by 2009. |
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Hip Cells For
Your Lungs
Tulane University has been granted $9.5 million to study the use of
adult stem cells to treat lung diseases such as emphysema, asbestos exposure
and cystic fibrosis. The hope is stem cells can repair the lining of
the lungs damaged by cystic fibrosis.
Clinical trials are expected to begin in two years. If tests prove successful
it should take only 90 days after bone marrow is extracted from patients to produce
stem cells for treatment.
The stem cells will be administered to the patient through an injection, IV or
nasal spray.
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A
Cider Mill Recipe!
Since the cider mill is on all of our minds. I though I would give you
a sweet and wonderful way to enjoy your favorite apples.
Apple Pie Cake |
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Serves 6 |
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2 |

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cups all-purpose flour |
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1 |

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cup packed light-brown sugar |
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2 |

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teaspoons ground cinnamon |
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1 |

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cup (2 sticks) unsalted butter |
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5 |

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pounds tart apples, such as Granny Smith
(about 12) |
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2 |

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tablespoons freshly squeezed lemon juice |
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1. In a large bowl, combine
the flour, brown sugar, and 1 teaspoon cinnamon. Using an
electric mixer or a pastry cutter, cut in the butter until
the mixture forms pea-size pieces. Press two-thirds of the
crumb mixture into the bottom and 1 inch up the sides of
a 9-inch springform pan. |
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2. Preheat the oven to 350°.
Core and peel the apples. Cut into thin slices, and place
in a large bowl. Toss the apple slices with the remaining
teaspoon cinnamon and the lemon juice. Arrange apples in
the prepared pan; they will come up over the sides of the
pan. Sprinkle the remaining crumb mixture over the apples. |
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3. Place pan on an aluminum
foil–lined baking sheet, and bake until cooked through
and golden brown on top, about 1 hour and 15 minutes. Run
a knife around the edge of the pan, and let the cake cool
in the pan to set. Serve, or refrigerate for 2 hours to set
more firmly. Serve at room temperature. |
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